Here we will inform you about clinically effective medicines. But these should be taken with just doctor prescriptions.
Minoxidil
Minoxidil is the first medicine which has approval from the FDA. It is solution and appliable on the head directly. Today it can be bought without prescription.
Minoxidil has been developed from minoxidil blood preasure medicine. It is taken orally but it has side effects on heart and blood circulation. So it should taken when there is no other medicine effects. Patients who have taken minoxidil,have pilosity on their bodies. If it is applied on head directly , it provides hair lenghth.
Minoxidil working mechanism isnot known exactly. But it is known that period of hair follicle growth circle is extended by the medicine.this situation affects by increasing diameter and lenght of hair that is miniature
Side Effects of Propecia:
Dicussions about propecia’s side effects which is one of the best treatment on men type hair loss are still continueing. On formal web site(
www.propecia.com) of Merk(producing company) the things below is written.
“on clinical research for propecia,it is observed that the medicine can be tolerated well. There is no any side effects on 98 % men. Very few men informed some side effects(1.8%) like decreased sexual desire,decreased sperm number. 1.3% of men informed that they have erection problems. After leaving medicine all complaints diappear. “
Merk says so but a little search on the net shows that number of sexual problems complaints is really very much
Although people took this medicine and cut using this medicine,still there are people who suffer from its side effects and there is a yahoo group called Finasterid (propecia)side effects(FİNASTERİD/PROPECIA’S SIDE EFFECTS):www.PropeciaSideEffects.com. The people who suffers from its side effects can be member here. According to this groups members since 2003,propecia’s permenant side effects are sexual problems,consantration problems,pain in their reproduction organs,growing problems on breast and often pee need.Group web page says:
“After cutting the propecia or proscar generally side effects clears out in e few days or a few weeks. But on some unlucky men these side effects go on during years and even maybe it becomes permenant.”
On the other hand some users have informed that they have black dots and lubrication on their forehands,although it isnnot said in the side effects. Two people informed that they have still acne problems after cutting propecia 6 month later,one person informed he has had still acne problem for 3 years.
Usage of Minoxidil
It should be taken twice a day. Medicine treatment is just effective when it is applied on the head directly and results just seen on applicable areas. So if patient has hair loss ,it should be applied on front areas. This is important.
Ayrıca bu ilaç mevcut olan saçların kalınlaşmasınıda sağlamaktadır. Sac köklerinin tükendiği tamamen açık bölgelerde yeni saç çıkarmamaktadır bu tip durumlarda sac ekimi kalıcı çözüm olur. .
5% formulation is twice more effective than 2%solution. But it causes hardening and brushing problems because of ingredients of propylene glycol
Usage For Women
Only 2% solution for women is good. Because women have more allergic system ,it may cause hypotension on women. Also women may have allergy more than man around applied areas. 5% solution increase the side effects so FDA hasnot approved this dose for women.
It may be caused to become hairy on women. ınstead of hair loss after cutting treatment, some hair is needed to clean with laser epilation.(
http://www.lazer-epilasyon.com/). This problem can be solved by not applying on forehead and temple areas. using 5% solution makes the issue more probable.
Finasteride
Man type hair loss or androgenetic alopesi(genetic man type hair loss) occurs because of dihidrotestesteron(DHT) in hair follicles which is on front, top head areas. DHT causes miniaturization in follicles by slowing hair growth or hair circle down. This hair starts to be shorter ,thicker slowly and then all hair is lost completely.( look at the hair loss reasons for men).
DHT occurs with 5-alfa reductase enzyme from testestesteron. Finasteride stops 5-alfa reductase enzyme. The figure shows how testestesteron in hair follicle turns into DHT
Finasteride’s label name has been approved for preventing hair loss by FDA.( http://www.fda.gov/cder/foi/nda/97/20180-S017 ) Finasteride reduces the level of DHT on head and head skin. Effects has been seen very well with these factors. Finasteride reduces the level of DHT nearly 70%. Level of serum testestesteron raises 9% but this is a normal percentage
Finasteride was used for the treatment of prostate first but effectiveness for hair loss has been found by accident. This reality was found in salinas town,Dominic republic in 1974 by McGinley. He observed the boys in salinas town. These boys have very little 5-alfa reductase. Also their DHT level is minimum and they did not have any prostate and hair loss problem in their life.
Researchers had had to find a medicine which stops 5-alfa reductase enzyme. And then they used this medicine for both prostate and hair loss. FDA approved this finasteride medicine (labeled 5-mg Proscar) to stop prostate for above 50 years old men. Five years later FDA approved 1-mg finasteride for hair loss treatment.
Researchs show that 90% people who has used finasteride don’t have any hair loss problem. In five years after fenasteride treatment ,increase on men hair has been seen 48%. Hair loss has not been seen 42% and only 10% men has not had any change on their hair.
When you compare them, 6% people’s hair who had placebo treatment, lengthened.there was no any change on 19% and there was hair loss on 75%.
Finasteride Effects on front areas of head
Finasteride is used for hair loss treatment on front and top areas. There are datas that it treats hair loss on front areas of head.
Usage of fenastreride
Fenasteride should be taken once before or after meals.ıt shoul be used one year and after this duration hair loss stops and new healthy hair appears. Its effects is seen in one year. In first 6 months you can see thining on your own hair, because hair loss still has been continuing. Maybe the reason for this is miniaturization. You need to be patient and use one year to see the good effects
Side effects of finasteride
It is not expected that it will have any side effects. After one-year regular finasteride usage,3,8% sujet people have sexual problems and 2,1% people who had placebo treatment have this kind of problems. After 5-year research results:sexual problem(0,3%),erection problems(0,3%),lessen of sperm number(0,0).
After starting the medicine,people sexual desire reduced. After the treatment and 58% people under cure ,this problem finished. After finishing treatment ,side effects will disappear slowly in a few weeks. When you cut finasteride ,only the hair with treatment will lose.
Other side effects
The 0,4% patient who used finasteride have sensibility and enlarging problems on their brest. But very few people have this kind of problems. And rarely people have miliaria,itching,urticaria,tumid lips, pain on testis problems.
Caution for pregnancy term
Finasteride is not suitable for pregnant women and the women who will be pregnant in the future. In pregnancy term women should avoid using this medicine because it causes diability for male babies’ sex organs by birth. The medicine can flow in body from the skin so all finasteride pills are covered with inpermeability cling film.
A woman who has a sexual affair with a man who has finasteride treatment,doesnot have any problem on her babby’s health
Finasteride usage after climacteric(menapoz) term
Merk did a study which indicates the effects of finasteride for women. At end of one year there was no hair growth so this study is cancelled. It is known that this situation isnot result of DHT enzyme. It results from aromatase enzyme effects. Also because of women’s low DHT level this situation results from body reaction.
Long term benefits of finasteride and possible risks
Fenasteride’s effects are seen both on hair loss and hairy areas. It is not effective on completely bald areas . although it causes regrowth of hair ,finasteride is effective to lessen and stop hair loss . results are seen in one year. Then in second year it stays same and then effects reduce. In fact there is no certain data for effects duration,but patients say they have seen effects 5 years.
When cutting medicine fenasteride effects ends.patients turns back the beginnig in 2-6 months.
Finasteride and hair cultivation
Finasteride can be combinated with hair cultivation. Desicion is given by a doctor.your doctor will show you a solution by analysing your age and amount of your hair loss
Generik Finasteride
Finasteride can be found in 5 mg generic formulation. But finasteride hasnot been found on the market until 2012. So the people who want to buy generic finasteride,can buy ¼ of 5mg pill from the chemist. Taking 1 mg finasteride everyday isnot effective like in the past and ıt is dangerous for pregnants.
İncreasing medicine dose
One of the most asking questions is about increasing fenasteride dose. There is no scientific data about side effects when increased dose. It is thought that There is no eny difference between 5mg and 1 mg fenasteride.
Finasteride patient watch
Over 50 year-old men should apply a doctor or an urologist before taking fenasteride. also it is advisable that these men should be checked up annually for prostate illness regularly. informations above are recommended for every men if they use finasteride or not. Other recommendations are up to your doctor.
Wrong thoughts about finasteride
Wrong: women cannot touch the medicine.
Right: pregnant women cannot touch the broken pill.
Wrong: it is effective just on top areas.
Right: it is effective on normal hair even on front hair
Wrong:finasteride reduces testestesteron.
Right: testestesteron(man hormone)doesnot reduce with medicine treatment.
Wrong: it has a lot of permenant side effects sexually
Right:2% men have sexul problem.after finishing treatment side effects disappear.
Wrong: when a pregnant's husband use this medicine the child have disability problems from birth
Right: sexual affair with a pregnant woman and a man who takes finasteride doesnot harm the baby.
Wrong:finasteride is a medicine for prostate.it doesnot stop hair loss.
Right:Finasteride is a medicine for prostate and for hair loss.ıt is learned by accident and since then it has been known its effects on hair growth.Dutasteride.
FDA approved this medicine for prostate in 2002 but Dutasteride isnot approved for hair loss treatment
Effects on hair growth
0.5mg Dudasteride reduces serum DHT(91%),skalp DHT(54%). Finasteride reduces serum DHT(71%),skalp DHT(38%).
When results compare with eachothers ,dudasteride is more effective than fenasteride for androgenetic alopesi (genetic man type hair loss).Because Amount of 5-alfa reductase isnot very high in hair follicles,it is not important that dudasteride cancels this enzyme.Dudasteride's effects are seen in order to reduce amount of serum DHT.
In 2006 olsen and his friends did a study which shows better sides of dudasteride than finasteride.this is published in American Dermatology Academy newspaper.http://www.liebertonline.com/doi/abs/10.1089/153082001753231036
Sprinolakton
It is used for hypotension.treatment usually starts with 25mg twice a day. It sends sodium from the body by saving potasium level and shows its effects.
Because potasium level is saved,amount of potasium level in blood increases.this makes the issue dangerous. so this medicine should be taken with doctor's control.
Spironolactone has anti-androgenetic effect and it is used for women hair loss.
